Bag Lifting Centrifuge for Biopharma Batch Solid-Liquid Separation

The Bag Lifting Centrifuge is designed for batch solid-liquid separation of filterable biopharma product solids after precipitation, crystallization, purification, or downstream processing.

In biopharma production, the separated material may include crystallized intermediates, precipitated product solids, purified active ingredient intermediates, fermentation-derived solids, or other valuable filter cakes requiring controlled washing and dewatering before further processing.

It is suitable for batch processes where complete product recovery, gentle handling, reduced cross-contamination risk, and hygienic product contact design are important.

• Crystallized pharmaceutical intermediate recovery
• Precipitated biopharma product separation
• Batch solid-liquid separation after downstream purification
• Filterable fermentation-derived product recovery
• API intermediate cake washing and dewatering
• Nutraceutical and biological active ingredient recovery
• Enzyme-related product solids after precipitation
• Fine chemical and pharmaceutical-grade crystal handling
• Product cake recovery before vacuum drying or tray drying
• Batch purification systems requiring removable filter bags

Biopharma product recovery often requires more than basic filtration. The separation stage must control product loss, wash quality, cake moisture, and cleaning between campaigns.

Typical requirements include:

• Recovery of valuable solid product with low hold-up
• Controlled removal of mother liquor or process liquid
• Batch washing to reduce residual salts or soluble impurities
• Reduced manual scraping inside the basket
• Gentle product handling during cake discharge
• Easier cleaning between product campaigns
• Hygienic product-contact materials
• Repeatable batch operation and traceable process control
• Flexible configuration for different product grades and batch sizes

The Bag Lifting Centrifuge supports these requirements through controlled centrifugal filtration, optional cake washing, spin drying, and removable bag-lifting discharge.

Peony provides centrifuge equipment and separation support for batch filtration, product cake washing, dewatering, and controlled discharge in biopharma downstream processing.

Process Evaluation

Our engineers evaluate:

• Product solid type and cake-forming behavior
• Particle size and filtration performance
• Slurry solids concentration and liquid properties
• Product purity and washing requirement
• Target moisture and downstream drying conditions

Equipment Selection

We help customers select:

• Suitable basket size and batch capacity
• Filter bag material and micron rating
• Filter screen and feed configuration
• Cake washing and spin-drying arrangement
• Bag lifting discharge system
• Product-contact material, surface finish, CIP option, and PLC automation level

The prepared product slurry enters the rotating basket lined with a filter bag and supporting filter screen.

Under centrifugal force:

1. Process liquid passes through the filter bag and is collected through the filtrate outlet.
2. Product solids are retained inside the basket.
3. A filter cake gradually forms on the inner surface of the filter bag.
4. Optional wash liquid is introduced to reduce residual mother liquor, soluble salts, or other process impurities.
5. High-speed rotation removes residual moisture from the product cake.
6. The machine stops after the programmed separation cycle is completed.
7. The filter bag containing the dewatered cake is lifted through the top discharge section.
8. The recovered product is collected or transferred to downstream drying, milling, screening, packaging, or further purification equipment.

The complete batch cycle can be controlled through PLC operation to maintain stable filtration, repeatable washing performance, and consistent product handling.

For biopharma applications, the equipment configuration should be selected according to the required product grade, cleaning procedure, containment level, and validation requirements.

To recommend a suitable Bag Lifting Centrifuge, please provide:

• Product name and material status
• Whether the feed is crystallized, precipitated, or purified solids
• Particle size distribution
• Slurry solids concentration
• Process liquid composition
• Feed temperature
• Batch volume or required capacity
• Target cake moisture
• Product purity requirement
• Cake washing requirement
• Product-contact material requirement
• Surface finish and CIP requirement
• Containment requirement
• Installation area and power supply
• Explosion-proof requirement, if applicable

Peony welcomes distributor and agent cooperation in biopharma processing, pharmaceutical intermediates, fermentation-derived products, nutraceutical ingredients, batch purification, and hygienic solid-liquid separation projects.

We support partners with centrifuge selection, process advice, filter bag matching, hygienic material configuration, cake washing design, CIP options, spare parts, and after-sales service.

Send us your customer’s product information, particle size, slurry solids content, process liquid composition, batch capacity, target moisture, washing requirement, and product-grade standard. Our team will help evaluate a suitable Bag Lifting Centrifuge solution.